Preparation of Liposomes Modified with Lipopeptides Using a Supercritical Carbon Dioxide Reverse-phase Evaporation Method

Preparation of Nonionic Vesicles Using the Supercritical Carbon Dioxide Reverse Phase Evaporation Method and Analysis of Their Solution Properties.

We have previously reported a new preparation method for liposomes using supercritical carbon dioxide (scCO2) as a solvent, referred to as the supercritical carbon dioxide reverse phase evaporation (scRPE) method. In our previous work, addition of ethanol to scCO2 as a co-solvent was needed, because lipid molecules had to be dissolved in scCO2 to form liposomes. In this new study, niosomes (non...

Formation and Physicochemical Properties of Liposomes Using a Supercritical Reverse Phase Evaporation Method

L-a-dipalmitoylphosphatidylcholine (DPPC) liposomes were prepared using supercritical reverse phase evaporation (scRPE) method. The effects of phospholipid structure, preparation pressure, and amount of ethanol on their physicochemical properties were examined using measurements of trapping efficiency, cloud point measurements, dynamic light scattering, and osmotic water transport studies. The ...

Vetiver Oil Extraction Optimization Using Supercritical Carbon Dioxide Fluid

Preparation of Inclusion Complex of Piroxicam with Cyclodextrin by Using Supercritical Carbon Dioxide

Forming complexes with cyclodextrins can enhance the dissolution rate, the stability, the solubility and the bioavailability of a drug. In this work, piroxicam/β-cyclodextrin complexes were prepared at solid state by means of supercritical carbon dioxide. The influence of temperature, residence time, water content and a ternary agent, L-lysine, were studied. The complex was characterized by Dif...

Preparation of PMMA/MWNTs Nanocomposite Microcellular Foams by In-situ Generation of Supercritical Carbon Dioxide

Nanocomposites containing poly(methyl methacrylate) (PMMA) and surface functionalized Multi-Walled Carbon Nanotubes (MWNTs) were synthesized. The dispersion of MWNTs in PMMA was characterized using Transmission Electron Microscopy (TEM).The synthesized nanocomposites were successfully foamed using a simple method based on the in-situ generation of supercritical carbon dioxide (CO2</sub...